[extropy-chat] neuro-regenerative/prophylactic in berberine compounds?

[Extropian Agroforestry Ventures Inc.]

http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&u=%2Fnetahtml%2FPTO%2Fsearch-adv.html&r=1&f=G&l=50&d=PG01&p=1&S1=astrocyte&OS=astrocyte&RS=astrocyte

United States Patent Application


20040097534
 Kind Code

A1
 Choi, Byung-Kil ;   et al.
                                                                May 20,
2004


Composition for the protection and regeneration of nerve cells
containing berberine
derivatives

                                   Abstract

Disclosed is a composition for protecting nerve cells, promoting nerve
cell growth and regenerating
nerve cells comprising berberine, derivatives thereof or
pharmaceutically acceptable salts thereof. The
composition has protective effects against apoptosis of neuronal stem
cells and differentiated neuronal
stem cells, an effect of inducing the regeneration of nerve cells, a
regenerative effect on neurites, a
neuroregenerative effect on central nerves and peripheral nerves, a
reformation effect on
neuromuscular junctions, and a protective effect against apoptosis of
nerve cells and a
neuroregenerative effect in animals suffering from dementia and brain
ischemia. Therefore, the
composition can be used as a therapeutic agent for the prevention and
treatment of neurodegenerative
diseases, ischemic nervous diseases or nerve injuries, and for the
improvement of learning capability.