[extropy-chat] antiaging paper

[Joao Magalhaes]

Hi,

As I've said many times, findings in yeast do not necessarily imply similar 
findings in mammals. There are many ways to extend lifespan in yeast and 
yet these have not been implicated in mammalian aging--except perhaps 
caloric restriction but even so the mechanisms of CR in yeast and rodents 
appear to be different. Now, you do mention that the lifetime of rats was 
extended by 50% but that is not in the papers you cite. Where did you read 
the results from rats? There have been studies with SOD2 in mice and rats 
but, as far as I know, these have NOT extended normal lifespan. You can 
check out:

http://genomics.senescence.info/genes/entry.php?hugo=sod2

All the best,

Joao

At 10:14 AM 28/9/2004, you wrote:
>JCB, Sept. 27
>http://www.jcb.org/cgi/content/abstract/166/7/1055
>and also
>http://www.genetics.org/cgi/content/abstract/163/1/35
>
>It seems that the above Italian talents (in USA),
>and especially Valter Longo, found something interesting.
>At least there are several newspapers saying
>that today, here. Yeats lifetime extended 5 times!
>Rats lifetime extended by about 50%. Aging mechanism
>seen as part of (past but also *present*) evolution.
>And so on. But I do not understand this stuff at all,
>so I'm just pointing it out to the estropicos.
>s.
>
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