[extropy-chat] Resveratrol oral effectiveness confirmed in animals

Gary Miller aiguy at comcast.net
Wed Sep 7 18:26:05 UTC 2005


>> SOURCE:International Journal Molecular Medicine 16:533-540, 2005 

Dealcoholized red wine containing known amounts of resveratrol suppresses
atherosclerosis in hypercholesterolemic rabbits without affecting plasma
lipid levels.
Wang Z, Zou J, Cao K, Hsieh TC, Huang Y, Wu JM. 

Department of Cardiology, The First Affiliated Hospital, Nanjing Medical
University, Nanjing 210029, P.R. China. 

Moderate consumption of red wine is associated with a reduced risk of
coronary heart disease (CHD). This phenomenon is based on data from
epidemiological observations known as the French paradox, and has been
attributed to CHD-protective phytochemicals, e.g. resveratrol in red wine.
Since red wine also contains alcohol, it is conceivable that alcohol
interacts with resveratrol to elicit the observed cardioprotective effects.
>>

Has anyone found any human trials published or underway?

The supplement is a bit expensive and I don't want to be wasting money on
the next magic bullet unless it has a good probability of being effective.

I'd also like to see a study on animals/humans with existing blockage to see
if there's any reversal.

Sounds like a study on humans would be difficult ethically to run because
you'd have to deprive the participents from statins which lower cholesterol
or you'd contaminate the results.

People like myself who have tried all the statins and were taken off due to
danger indicators in the subsequent blood tests, could potentially benefit
greatly from such a supplement. 







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