[ExI] Gout and meat adaptations
js_exi at gnolls.org
Wed Apr 20 12:47:22 UTC 2011
I'll get back to Harvey's stuff in a bit, but:
> Humans radiated out of Africa long enough ago that they
> would have been time for digestive systems to evolve variations dependent on
> where the genetically isolated subgroups of humans evolved. For instance,
> the Inuits have developed the ability to subsist entirely on meat, whereas
> the Europeans tend to develop gout and ketosis if we try that.
I love you, Spike, but there are a couple problems here.
First, the idea that meat (or purines in general) cause gout is an old
myth. Fructose is the primary driver of blood uric acid, and,
"Men who consume two or more sugary soft drinks a day have an 85% higher
risk of gout compared with those who drink less than one a month, a
study suggests." ... "Diet soft drinks did not increase the risk of gout
but fruit juice and fructose rich fruits (apples and oranges) were
associated with a higher risk, the researchers said."
And an excellent overview of the real issues, which are fructose,
***high insulin***, and underhydration (includes links/references):
A severe gout sufferer I know said that he has not had a single gout
attack -- not even a tingle -- since going on a high-fat paleo diet.
Second, the idea that there is a special Inuit adaptation to meat-based
diets is unsupported by any evidence with which I'm familiar. The ApoE
variation that allows us to process dietary fat much better than
chimpanzees is millions of years old:
Pardon the website, but here's another instructive article about
non-Inuit eating meat-based diets (the magazine it's from is otherwise
behind a paywall), i.e. Vilhjalmur Stefansson:
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