[ExI] PaleoCRON?

Jones Murphy morphy at alumni.caltech.edu
Tue Apr 26 19:46:47 UTC 2011

For those prone to type II diabetes(by far the most common type), the
blood sugar benefits of CR prevent and/or cure their diabetes entirely
if CR onset is early enough. That's worth a couple of decades. Similar
is true for those prone to cardiovascular disease. Those are two big
groups, accounting for about half of all deaths between them.

On Tue, Apr 26, 2011 at 9:39 PM, Eugen Leitl <eugen at leitl.org> wrote:
> On Tue, Apr 26, 2011 at 12:22:52PM -0700, Max More wrote:
>> We really don't yet know how much of a boost CR will give to the human life
>> span. Note that both Aubrey de Grey and Michael Rose expect that CR produces
> I would be very, very surprised if it gives you 20, maybe 30 years
> just as outliers.
>> results that are closer to absolute than relative to the species.
>> This means, if they are correct, that humans will enjoy a quite modest
>> extension, nothing like decades.
> I think CR as part of a lifestyle in absence of pathologies can result
> in one to three decades at high quality of life, similar to current
> supercentenarians. Nothing to write home about, unfortunately.
>> I agree with Stefano about the downsides to moderate-to-severe CR. On the
>> other hand, I see all kinds of good reasons to practice mild-to-modest CR in
>> the form of intermittent fasting and portion control as part of a NeoPaleo
>> approach. Doing fasting while on a NeoPaleo diet is easier, because blood
>> sugar levels are more stable and hunger less acute.
> Most of current jobs today are moderately stressful sedentary rodent
> pushing. It's hard to reconcile a healthy lifestyle with that, with
> CR being part of the package.
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