[ExI] bexarotene papers

spike spike66 at att.net
Thu Aug 9 23:25:52 UTC 2012


-----Original Message-----
From: extropy-chat-bounces at lists.extropy.org
[mailto:extropy-chat-bounces at lists.extropy.org] On Behalf Of BillK
...

>...I agree. The first article is a cautionary warning to doctors.  No
further testing has been done. The one mouse study has not even been
replicated yet, so it could be a fluke result.  BillK
_______________________________________________


Oy vey, the LA Times today replicated a mistake from early in the cycle back
in February.  An order of magnitude error was made by someone writing "per
day" instead of "per month."  I have seen this error pop up hundreds of
times, and it may have slain patients by now.  

http://www.latimes.com/health/boostershots/la-heb-alzheimers-drug-ethics-201
20809,0,2927327.story

".Second, patients and their advocates must consider whether it is fair for
doctors to begin writing prescriptions for bexarotene for patients with
dementia. The unreimbursed cost of treating an Alzheimer's disease patient
with bexarotene -- anywhere between $1,200 and $2,500 per day out-of-pocket
by one estimate -- would make this a treatment option only for the very
wealthy."

Imagine a really wealthy family with an AD patient, reads the above comment,
says to his son, Junior, you somehow know how to score all kinds of vile
dope to poke into yourself, so take this $10k, go use your contacts, bring
me that much Targretin and don't tell me how or where you got it.  Junior
takes off, comes back an hour later with $10k in Targretin, dad shovels all
of it down grandma's throat over the next 4 to 6 days, patient mysteriously
expires from an acute overdose of bexarotene resulting in massive multiple
organ failure.  Newspapers need to be very careful about propagating
misinformation.

Eeesh.

spike




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