[ExI] good bexarotene article

spike spike66 at att.net
Mon Feb 13 17:07:06 UTC 2012


I have learned that a typical therapeutic dosage of bexarotene for cancer
patients costs about 1200 USD per month, which is manageable, less than a
fifth as much as a typical memory care facility.  The other good news is
that the patent for bexarotene expires this year, so there might be a bunch
of generics show up soon.  

I expect those labs all over the world which have Alzheimer's mice are
scrambling to reproduce the results reported last week, so we should be
hearing from them soon.  I don't know how long it takes for these kinds of
tests to run.  

I also want to hear from those few labs which have natural Alzheimer's
chimps.  Chimps are expensive to keep, so there aren't many of them, but
their blood/brain barrier is very similar to humans.  There are zoos that
keep chimps and bonobos well into their dotage, most claiming they are the
original Tarzan's companion, Cheetah.

Unanswered still is if bexarotene works at lower dosages than are typical
for cancer patients, or if it works at all in humans against Alzheimer's, or
if for some odd reason it helps only genetically linked early Alzheimer's
patients.

spike



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