[ExI] [GRG] Biomarkers and ageing: The clock-watcher (fwd)

[Tomasz Rola]

----- Forwarded message from Pedro Fernandes <pfern at igc.gulbenkian.pt> -----

Date: Sat, 26 Apr 2014 10:00:15 +0100
From: Pedro Fernandes <pfern at igc.gulbenkian.pt>
To: Gerontology Research Group <grg at lists.ucla.edu>, Paul Wakfer
	<paul at live120plus.com>
Cc: grg at lists.ucla.edu
Subject: Re: [GRG] Biomarkers and ageing: The clock-watcher


Very much so.

As you rightfully point out, blood samples do exist already, that can
enable a wide range assessment of the value of the biomarker-based
ageing rate estimates for a relatively low cost. Carefully chosen
cohorts will allow for statistical differences to emerge from the
data. Grouping data by Haplotype, lifestyle, diets, etc. can reveal
important hidden differences.

Pedro
-- 
Pedro Fernandes
Instituto Gulbenkian de Ciência
Apartado 14
2781-901 OEIRAS
PORTUGAL
Tel +351 21 4407912
http://gtpb.igc.gulbenkian.pt



Quoting Paul Wakfer <paul at live120plus.com>:

> This paper from Steve Horvath is *enormously* important!
> 
> There is now a reliable biomarker for human aging rate and all
> human aging interventions from now on should employ it to ascertain
> the effectiveness of the intervention. In effect, many of the mouse
> lifespan studies can now be repeated for humans (at least the ones
> that were safe and showed positive results). With the accuracy of
> this biomarker, given reasonable size human control and
> intervention cohorts, 5-10 years should be sufficient to see a
> significant difference, if one exists. A start can be made by using
> the saved blood from the many longitudinal studies of various
> groups that have been done worldwide to see if there are some
> correlations between various lifestyle parameters and aging
> *deceleration* as measured by the Horvath biomarker test.
> 
> I can hardly wait to see these new results appearing!
> 
> --Paul Wakfer
> http://Live120Plus.com
> 
> On 04/25/2014 10:02 AM, Pedro Fernandes wrote:
>> 
>> Interesting paper
>> 
>> http://www.nature.com/news/biomarkers-and-ageing-the-clock-watcher-1.15014?WT.mc_id=TWT_NatureNews
>> P. Fernandes
>> 
> 
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