[ExI] Cryonics punched cards and the brain
johnkclark at gmail.com
Sun Jan 24 16:30:07 UTC 2016
On Sun, Jan 24, 2016 at 7:49 AM, Anders Sandberg <anders at aleph.se> wrote:
> Neat. Generally LTP is seen as the first of a longer cascade of fixation
> of memories. Most research has been about cellular skeleton changes, but
> perineuronal nets might also work.
> It might actually be a good experiment for cryonics to see what the
> process does to these nets. (I think John mixed up the perioneuronal net
> (protein networks) with perineuronal space in the sleep reference. )
As I understand it
the extracellular matrix
the space between brain cells
and that is where the
is located along with a lot of fluid, and the volume of the
changes a great deal between sleep and wakefulness so the net must be
tough enough to resist damage even when things get crowded. But I'm no
expert on this so I may have misunderstood.
> Incidentally, the Sejnowski lab had a nice result on the distribution of
> synaptic strengths:
> Bartol, T. M. Jr. Bromer, C. Kinney, J. P. Chirillo, M. A. Bourne, J. N.
> Harris, K. M. Sejnowski, T. J.
> Nanoconnectomic upper bound on the variability of synaptic plasticity,
> eLife, 4:e10778, 2015
> They show that each synapse stores at most about 4.7 bits. While their
> press material claims this is "an order of magnitude more" than previous
> estimates, the actual estimate most people have been doing is about one
> bit, so the difference isn't dramatic. But doing nanoconnectomics is an
> awesome method.
I wish we knew how much redundancy there is in the brain, biological
operations are not nearly as reliable as the electronic operations we use
in computers so I would guess there must be a lot of
to ensure accuracy.
John K Clark
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