[ExI] https://www.sciencedirect.com/science/article/pii/S0006291X20303661 Stem cells reprogrammed

Diego Saravia dsa at unsa.edu.ar
Wed Mar 25 13:09:16 UTC 2020

For the first time, scientists have reprogrammed the stem cells of a
114-year-old woman, the oldest donor to date. After first transforming
cells from her blood sample into induced pluripotent stem cells (iPSCs),
the researchers then generated mesenchymal stem cells, which help to
maintain and repair tissues like bone, cartilage and fat. "We set out to
answer a big question: Can you reprogram cells this old?" says stem cell
biologist Evan Snyder at Sanford Burnham Prebys Medical Discovery Institute
in California. "Now we have shown it can be done, and we have a valuable
tool for finding the genes and other factors that slow down the aging
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