[ExI] AstraZeneca's Phase 3 trial

[Dylan Distasio]

mRNA vaccines look promising because they avoid these issues and can be
ramped up and manufactured in volume.  They are also of course new tech
with no long history of vaccine trials beyond Covid.

However, both require heavy cooling to remain viable.  Moderna's needs
-4C.  Pfizer's needs a very impractical -60C although they've designed
custom dry ice carriers for shipment.   Any research lab will have a
freezer that cold, but I doubt there are many in clinical settings.
Logistics may be a challenge.

On Wed, Sep 9, 2020, 8:18 AM John Clark via extropy-chat <
extropy-chat at lists.extropy.org> wrote:

> The AstraZeneca Phase 3 trial of its COVID-19 vaccine has just been halted
> because one individual got a severe spinal infection that may have been
> caused by the vaccine. AstraZeneca used a weakened but living chimpanzee
> virus similar to the common cold as a vector to get DNA into cells and make
> them produce COVID-19 antigens, the Russian vaccine also uses this method
> but other vaccine candidates do not use a live virus.
>
> John K Clark
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> extropy-chat at lists.extropy.org
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