<a href="http://www.wired.com/news/medtech/0,1286,69701,00.html?tw=rss.TOP">Wired News</a>: Led by University of Missouri-Columbia biological physics professor
Gabor Forgacs and aided by a $5 million National Science Foundation
grant, researchers at three universities have developed bio-ink and
bio-paper that could make so-called <a href="http://organprint.missouri.edu/">organ printing</a> a reality.Here's how it works: A customized milling machine prints a small sheet
of bio-paper. This "paper" is a variable gel composed of modified
gelatin and <a href="http://www.pharmacy.utah.edu/medchem/prestwich/Hyaluronan.html">hyaluronan</a>,
a sugar-rich material. Bio-ink blots -- each a little ball of cellular
material a few hundred microns in diameter -- are then printed onto the
paper. The process is repeated as many times as needed, the sheets
stacked on top of each other.Once the stack is the right size -- maybe two centimeters' worth of
sheets, each containing a ring of blots, for a tube resembling a blood
vessel -- printing stops. The stack is incubated in a bioreactor, where
cells fuse with their neighbors in all directions. The bio-paper works
as a scaffold to support and nurture cells, and should be eaten away by
them or naturally degrade, researchers said.<br>