Almost all of us still have the capability. I believe there are some rare genetic diseases that may involve defects in the uncoupling proteins or the related genetic factors that result in defects in their activation (time to go look at OMIM I suppose...). The number of proteins (I think there are at least 3) didn't become clear I think until the HGP was complete. They are still unraveling what turns them on and off last time I ran across a discussion. Wikipedia has brief articles on thermogenin and thermogenesis that are related. A more detailed search would involve looking at Medline abstracts involving UCP1, UCP2, UCP3, etc. (do I have to do *all* the biochemistry work around here.... :-?!?)
<br><br>But remember, I said that enabling the uncoupling proteins is likely to result in increased free radical production...<br><br>R.<br><br><div><span class="gmail_quote">On 2/2/06, <b class="gmail_sendername">Adrian Tymes
</b> <<a href="mailto:wingcat@pacbell.net">wingcat@pacbell.net</a>> wrote:</span><blockquote class="gmail_quote" style="border-left: 1px solid rgb(204, 204, 204); margin: 0pt 0pt 0pt 0.8ex; padding-left: 1ex;">--- ben <
<a href="mailto:benboc@lineone.net">benboc@lineone.net</a>> wrote:<br>> It seems likely that this BAT could be prodded into action in adults,<br>> or<br>> maybe a 'BAT transplant' would be feasible.<br><br>That's the line of thinking that got me started on this in the
<br>first place, some time ago. Given recent technical advances -<br>might it be feasable to differentiate adult stem cells into BAT?<br>(So, turning fat into a fat burner.0<br>_______________________________________________
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