<h2 style="">Suspended-animation cold sleep achieved in lab</h2>Starship freezer podules (well, medical apps)
foreseen
<p class="byline">By <a href="http://forms.theregister.co.uk/mail_author/?story_url=/2010/06/11/suspended_animation_in_lab/" title="Send email to the author">Lewis Page</a> • <a href="http://search.theregister.co.uk/?author=Lewis%20Page" class="more-by-author" title="More stories on this site by Lewis Page">Get
more from this author</a></p>Top boffins in the States believe that they may be on the track of a
way to place living human beings into suspended animation, allowing them
to survive long periods effectively frozen before being "reanimated"
with no ill effects.<div name="body" id="body">
<p>Dr Mark Roth, based at a Seattle cancer laboratory, got interested in
suspended animation after looking at several cases where this has
occurred spontaneously in humans.</p>
<p>One well-known case is that of Canadian toddler Erica Nordby, who
wandered outside in the winter of 2001 wearing only her nappy. In the
bitter cold her heart stopped beating for two hours and her body
temperature plunged to just 16°C* before she was rescued, warmed - and
came miraculously back to life, despite having literally frozen to
death.</p>
<p>In another case a Japanese man, Mitsutaka Uchikoshi, fell asleep on a
snowy mountainside in 2006. He was found 23 days later with a core body
temperature of just 22°C*. He too was successfully reanimated having
suffered no appreciable ill effects.</p>
<p>"There are many examples in the scientific literature of humans who
appear frozen to death. They have no heartbeat and are clinically dead.
But they can be reanimated," says Dr Roth.</p>
<p>Roth and his colleagues wondered how it is that some people can enter
a state of frozen suspended animation and then recover from it safely,
whereas in general such a change of body temperature is deadly.</p>
<p>The scientists now think they may be on the track of an answer,
having learned how to perform the same trick reliably with other
lifeforms; in this case yeasts and nematode worms.</p>
<p>Yeasts and worms, like humans, will normally simply die if they are
chilled down past a certain point. But Roth and his colleagues have
found that if the little creatures are starved of oxygen before turning
on the cold, they will go into suspended animation from which they
recover on warming and go on to live normal yeasty or wormy lives.</p>
<p>Here's an illustrative vid from the team:</p>
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</object></p>
<p>"We wondered if what was happening with the organisms in my
laboratory was also happening in people like the toddler and the
Japanese mountain climber," says Roth. "Before they got cold did they
somehow manage to decrease their oxygen consumption? Is that what
protected them? Our work in nematodes and yeast suggests that this may
be the case, and it may bring us a step closer to understanding what
happens to people who appear to freeze to death but can be reanimated."</p>
<p>The idea here is not so much to place people into deep freeze in
order to endure lengthy interstellar voyages, a staple idea in science
fiction but unlikely in the near future (humanity is struggling even to
assemble a Mars mission right now).</p>
<p>Rather, Roth and his colleagues think that their work might lead to
techniques that would let paramedics or doctors "buy time" for severely
injured or ill patients by putting them into suspended states like those
achieved by Nordby and Uchikoshi. Then, once the underlying problem had
been fixed, they could be reanimated.</p>
<p>Full details of the research are published online ahead of print in
the journal <em>Molecular Biology of the Cell</em>, <a target="_blank" href="http://www.molbiolcell.org/cgi/content/abstract/E09-07-0614v1">here</a>
(subscription link). ®</p>
<p>*Normal adult core body temperature is 37°C, a trifle lower for kids.
Any variation of much more than a degree is cause for serious concern;
several degrees' sustained variation is a probably fatal medical
emergency of one kind or another.</p>
</div><a href="http://www.theregister.co.uk/2010/06/11/suspended_animation_in_lab/">http://www.theregister.co.uk/2010/06/11/suspended_animation_in_lab/</a><br>