<html><body><div style="color:#000; background-color:#fff; font-family:arial, helvetica, sans-serif;font-size:12pt"><div style="RIGHT: auto"><SPAN style="RIGHT: auto"><SPAN style="RIGHT: auto">It depends on what the background rate of change is and what kind of impact these changes have. E.g., imagine a SNP change that has zero impact because it's for a structural protein for something that's rarely produced and it codes for part of the structure that is tolerate of having many different sequences of amino acids. In that case, wild changes in it wouldn't have much impact on the phenotype and it's likely drift would be the norm... (Or this is my lay understanding.:)</SPAN></div>
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<DIV style="RIGHT: auto"><SPAN style="RIGHT: auto">That said, if such a change were "common" -- if few or no humans ten thousands years ago had it and now all or almost all humans have it -- I'd be suspicious that there's something else going on here.</SPAN></DIV>
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<DIV style="RIGHT: auto"><SPAN style="RIGHT: auto">Regards,</SPAN></DIV>
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<DIV style="RIGHT: auto"><SPAN style="RIGHT: auto">Dan</SPAN></DIV></SPAN></DIV></DIV></DIV>
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<DIV style="BORDER-BOTTOM: #ccc 1px solid; BORDER-LEFT: #ccc 1px solid; PADDING-BOTTOM: 0px; LINE-HEIGHT: 0; MARGIN: 5px 0px; PADDING-LEFT: 0px; PADDING-RIGHT: 0px; HEIGHT: 0px; FONT-SIZE: 0px; BORDER-TOP: #ccc 1px solid; BORDER-RIGHT: #ccc 1px solid; PADDING-TOP: 0px" class=hr contentEditable=false readonly="true"></DIV><B><SPAN style="FONT-WEIGHT: bold">From:</SPAN></B> "kellycoinguy@gmail.com" <kellycoinguy@gmail.com><BR><B><SPAN style="FONT-WEIGHT: bold">To:</SPAN></B> ExI chat list <extropy-chat@lists.extropy.org><BR><B><SPAN style="FONT-WEIGHT: bold">Sent:</SPAN></B> Friday, July 29, 2011 1:39 PM<BR><B><SPAN style="FONT-WEIGHT: bold">Subject:</SPAN></B> Re: [ExI] People are the same?/was Re: No Moon Bases Needed<BR></FONT><BR>
<DIV style="RIGHT: auto" id=yiv612100008>I don't have access to my computer today... But I recall one of the TED speakers saying there had been 5000 genetic changes in the common human genome since agriculture...<BR><BR>It may not amount to very much... I don't know.<BR><BR>Kelly<VAR id=yui-ie-cursor></VAR></DIV></DIV></DIV></div></body></html>