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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> extropy-chat-bounces@lists.extropy.org [mailto:extropy-chat-bounces@lists.extropy.org] <b>On Behalf Of </b>Isabelle Hakala<br><b>Sent:</b> Saturday, February 11, 2012 1:00 PM<br><b>To:</b> ExI chat list<br><b>Subject:</b> Re: [ExI] good bexarotene article<o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='color:#1F497D'>>…</span>How difficult would it be to find someone with Alzheimer AND the particular type of cancer that it is used for... that seems as though there must be SOMEONE out there... and odds are they would be willing to take it for their cancer... esp if it might help their Alzheimers... Seems as though that would be an easy enough test. It isn't like they would say 'oh... you can't take this drug for your cancer because it might help your Alzheimers too, and that would be experimenting'.<br><br>-Isabelle<br><br><br><o:p></o:p></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Ooooh good thinking, thanks Isabelle. It should be easy to find cancer patients with Alzheimer’s. The question now at hand is if that information about their medical history is available.<o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>This goes back to a discussion we had here a dozen years ago. There should be a database somewhere, where people can dump medical information, while stripping out identities, so that we can find this kind of signal in the noise. I am surprised something like that doesn’t exist somewhere. We could maintain patient privacy while still perhaps filtering out these oddball correlations: a certain type of cancer patient doesn’t seem to get Alzheimer’s or has a lower rate than the general population. The signal could have been sitting there for years, undiscovered because we have no systematic way to find it among the deep piles of data, hidden away to maintain patient privacy. <o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Perhaps if we had a group of volunteers who are willing to dump everything about their medical history on the web, that might help. I would sign up, but my medical history is pretty boring: one kidney stone 15 years ago, and nothing else has ever gone wrong.<o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>spike <o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p></div></body></html>