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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>>…</span></b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> <b>On Behalf Of </b>Adrian Tymes<br><b>Subject:</b> Re: [ExI] FDA Tells Google-Backed 23andMe to Halt DNA Test Service<o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p><div><div><div><p class=MsoNormal>On Thu, Nov 28, 2013 at 9:47 AM, Rafal Smigrodzki <<a href="mailto:rafal.smigrodzki@gmail.com" target="_blank">rafal.smigrodzki@gmail.com</a>> wrote:<o:p></o:p></p><p class=MsoNormal>### The real issue is that the FDA imposes enormous arbitrary costs<br>(measured in hundreds of billions of dollars) on me and other<br>consumers by demanding those, as you say, "simple" proofs of accuracy<span style='color:#1F497D'>… Rafal</span><o:p></o:p></p><div><p class=MsoNormal><o:p> </o:p></p></div><div><p class=MsoNormal style='margin-bottom:12.0pt'><span style='color:#1F497D'>>…</span>The provided justification is that, absent these proofs, collective costs to said consumers would be far higher, since each consumer would independently have to verify what's accurate - and, more often, suffer when their own research fell short<span style='color:#1F497D'>… Adrian<o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Idea: set up a government agency to collect patient feedback on the efficacy of a medical device, or anything medical: pills, potions and lotions. Let them collect the data from anonymous contributors, and any negative reaction to the medications, have them fill out questionnaires and so forth, especially valuable if the patients are willing to volunteer what other medications they are taking. Then let the FDA do its data-mining magic to sift the data and find oddball correlations, such as taking cortium hydrochloroplazinate while on paxil and drinking excessively causes increased risk of masturbation-related injury, that sort of thing.<o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>They could create a publicly available database with efficacy ratings of the various pills, potions and lotions.<o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>What we could do is to let willing proles be the beta testers, then let the FDA decide which medications work for what ailments. I recognize the risk of intentional corruption of the database for profit and all the other risks, but it would likely be an improvement over what we have now, which is a system with crazy high costs to prove what might be a very subtle signal.<o:p></o:p></span></p><p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>spike<o:p></o:p></span></p></div></div></div></div></div></body></html>