<div dir="ltr"><div>I forwarded your questions to an acquaintance who's a researcher in the field. Here's what she said:<br><br>---BEGIN FORWARDED MESSAGE---<br>Tell Natasha that I've been working on aging and seniors for about
20 years now, so my information is an amalgam of information gleaned
largely from clinical and academic sources, but it's come from so many
sources I couldn't possibly list them. <br><div class="im">
<br>>Does anyone have updated science facts on the
human body/brain as a whole that looks at:<br>
><br>
> 1. When does the body starts aging (conflicting views suggest directly after puberty, others say 20-ish);<br><br></div></div>The
aging process starts with chromosome chains, each of which is capped by
a telomere (kind of like the aglet on the ends if shoelaces). Each
telomere is preprogrammed from birth to indicate (among other things)
how often this particular chromosome chain can reliably multiply before
aging and losing some of the contents. There's no specific age to each
telomere, but generally they start affecting the chromosomes around
one's early 20's. The good news is that most of the telomeres continue
their healthy reproduction of chromosomes until very late in life.<div class="im"><br>
<div>
> 2. When does the body start preparing for death (conflicting
views, and some suggest after menopause and andropause); <br><br></div></div><div>Depends
on what's meant by "preparing for death." One could say that it starts
when the first chromosome chain misbehaves and who knows when that is.
Different parts of the body age at different rates, and disease or
malfunction can affect that. In many cases, people know when their body
is getting ready to die. My mother knew that she
was dying more than a month before she actually did. <br>
</div><div class="im"><div><br>> 3. If the body regenerates itself every seven years, how does
this affect the aging process (most views reference limited ability to
create daughter cells is the point of preparation for death) and if
neurons in the cerebral cortex are never replaced, why is there a broad
statement that the body regenerates itself every seven years?<br><br></div></div><div>To
say that the body regenerates itself every seven years is too broad a
statement. Some parts do, some don't. Each time there is cell division,
there is a possibility that some new gene combination will occur that
subtly changes how the body works. Science doesn't yet know how that
works, but have observed the changes in the lab. The ability to
generate new body parts (e.g., an ear) from skin stem cells illustrates
the phenomenon. <br>
<br></div><div>Please tell your friend that the phrases "fight aging"
and "anti-aging" are markers for variations on snake oil. Most of the
things sold or advocated with those phrases in the descriptions are
untested, unapproved, and generally unbelievable. There's a whole
industry that's grown up around those and similar phrases to take in the
gullible with money to spend.<br>
<br></div>As to where to look for credible information, look for
clinical research papers or courses on aging by degreed professors.
AARP's research section is a good place to start. <div class="gmail_extra">---END FORWARDED MESSAGE---<br><br></div><div class="gmail_extra">In addition to that "untested, unapproved, and generally unbelievable", I would add, "and most of those that have been tested have been shown not to work, but are sold as life extenders anyway". Until there's wide scale enforcement on truth in advertising here, the market is unfortunately almost 100% fraud.<br>
<br></div><div class="gmail_extra">Of course, we care about that "almost". But we can't ignore the facts on the ground, if we wish to be effective.<br></div></div>