<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"><head><meta http-equiv=Content-Type content="text/html; charset=utf-8"><meta name=Generator content="Microsoft Word 14 (filtered medium)"><style><!--
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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> extropy-chat [mailto:extropy-chat-bounces@lists.extropy.org] <b>On Behalf Of </b>Adrian Tymes<br><b>Sent:</b> Thursday, July 02, 2015 7:14 PM<br><b>To:</b> ExI chat list<br><b>Subject:</b> Re: [ExI] digital resurrection of a genome<o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p><div><div><div><p class=MsoNormal>On Thu, Jul 2, 2015 at 6:41 PM, spike <<a href="mailto:spike66@att.net" target="_blank">spike66@att.net</a>> wrote:<o:p></o:p></p><div><p class=MsoNormal><o:p> </o:p></p><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='color:#1F497D'>>>…</span>Suppose a guy is married three times and has at least a couple (but as many as four) girlfriends on the side, and it becomes apparent that he is the father of at least 25 children<span style='color:#1F497D'>…</span>In theory, with sufficient persistence and determination, those descendants could <span style='color:#1F497D'>…</span>reconstruct the entire genome of the long-perished prolific ancestor.<o:p></o:p></p></div></div><div><p class=MsoNormal><o:p> </o:p></p></div><div><p class=MsoNormal><span style='color:#1F497D'>>…</span>What happens if any of the guy's genes did not make it into anyone still alive at the time of comparison? (Most simply, one gene happening in all 25 cases to not make it into the fertilizing sperm.) <o:p></o:p></p></div></div><p class=MsoNormal><span style='color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>I don’t know Adrian. Do we have any hipsters in that area? <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Are there any computer sims we might reference? I should know this, but I don’t. Oh the shame, the ignominy is nearly more than I can bear.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>In this particular case, we think at least 20 of the offspring have living descendants, and of those, at least 16 offspring have descendants who have done a DNA test. We have a buttload of data on this guy at least one famous descendant (Chuck Yeager) and possibly a second ( John Forbes Nash (may he rest in peaceful equilibrium (haven’t been able to confirm it.)))<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>spike <o:p></o:p></span></p></div></div></div></body></html>