<div dir="ltr"><br><div class="gmail_extra"><br><div class="gmail_quote">On Thu, Aug 27, 2015 at 12:22 AM, Brian Manning Delaney <span dir="ltr"><<a href="mailto:listsb@infinitefaculty.org" target="_blank">listsb@infinitefaculty.org</a>></span> wrote:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><span>El 2015-08-26 a las 17:50, William Flynn Wallace escribió:<br>
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I'll answer that: P.W. Piri-Tarino, etc. "Meta analysis of<br>
Prospective Cohort studies<br>
Evaluating the Association of Saturated Fat with Cardiovascular<br>
Disease." American Journal of clinical Nutrition 91, no.3 March 2010<br>
535-46 340,000 Ss, 21 studies<br>
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Take a look at the Medline entry for that study, and look at the comments, as well as -- if you have time; there are 21 -- the reviews among the 70 citing papers:<br>
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<a href="http://www.ncbi.nlm.nih.gov/pubmed/20071648" rel="noreferrer" target="_blank">http://www.ncbi.nlm.nih.gov/pubmed/20071648</a><br>
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I wouldn't base my dietary choices on the conclusions reached.</blockquote><div><br></div><div>The U.S. government's recommendations for the American people to change their diets and avoid saturated fat and dietary cholesterol was based on essentially no evidence at all: one scientist's contentious hypothesis, never confirmed or test, but nonetheless, used as the basis for nutritional advice for the past 40 years.</div><div> </div><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"> I'm not saying dietary SFA is evil; rather: we don't know. If I had to guess I'd say one would be better off with complex carbs and lots of MUFA and some PUFA. </blockquote><div><br></div><div>Based on what evidence?</div><div> </div><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex">(It's also likely that SFA is a problem only above a certain chain length.) </blockquote><div><br></div><div>Why do you think so?</div><div><br></div><div>Jason</div><div><br></div><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex">Can't wait until we have richer computer models of human physiology and can do virtual trials!<br>
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James, how amazingly fortunate you are to have gotten a whole genome scan! And thank you for participating in the PGP. Your participation benefits us all. (I'm still trying to decide which health data tracking/storage system is best so that I can upload my health data.)<br>
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I'm also testing blood glucose regularly. I'm less convinced we know how to interpret blood lipids, so I'm holding off on doing that frequently, but th science is pretty solid on the merits of keeping glucose down -- both avg. levels and spikes, possibly even very brief spikes (although CR rodents in the normal model of CR, where, for budgetary reasons, the animals are fed once a day, have huge, though fairly brief glucose spikes, but still live extremely long lives).<span><font color="#888888"><br>
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Brian</font></span><div><div><br>
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