<div dir="ltr"><br><div class="gmail_extra"><br><div class="gmail_quote">On Fri, Apr 15, 2016 at 11:37 AM, William Flynn Wallace <span dir="ltr"><<a href="mailto:foozler83@gmail.com" target="_blank">foozler83@gmail.com</a>></span> wrote:<blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr"><div style="font-family:'comic sans ms',sans-serif;font-size:small;color:rgb(0,0,0)"><span style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px"><br></span></div><div style="font-family:'comic sans ms',sans-serif;font-size:small;color:rgb(0,0,0)"><span style="color:rgb(34,34,34);font-family:arial,sans-serif;font-size:12.8px">Yes, I am quite convinced about that. Not only does fat not raise cholesterol but raised cholesterol may not be as dangerous as once thought. I am nearly sure about that one. One nutrition book I read was by a nurse who is on a 80% fat diet.</span></div><div style="font-family:'comic sans ms',sans-serif;font-size:small;color:rgb(0,0,0)"><br></div></div></blockquote><div> ### High cholesterol is without doubt dangerous, and I do not think that researchers overstated the degree of danger. Severe familial hypercholesterolemias are associated with a massively increased risk of stroke and myocardial infarction, and the garden variety age-related hypercholesterolemia is also a significant risk factor for these outcomes.</div><div><br></div><div>However, the story is a bit more complicated: While treatment with statins, which reduces cholesterol, is without doubt life-saving in the appropriate patient populations, other cholesterol-lowering drugs are for the most part useless or even harmful. This implies that age-related hypercholesterolemia may be a proxy for another pathological process (e.g. inflammation) that is responsible for bad outcomes and responds to statins, but is not affected by other hyperlipidemic drugs. So, if you have high cholesterol and otherwise meet criteria for statin treatment, you should be treated, regardless of whether statins work their magic through their impact on cholesterol or through other pathways. But there is no reason to waste money on non-statin drugs.</div><div><br></div><div>Rafał</div></div>
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