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<p>Interesting use of a classic drug/stain: memory enhancer.</p>
<p><a class="moz-txt-link-freetext" href="http://pubs.rsna.org/doi/10.1148/radiol.2016152893">http://pubs.rsna.org/doi/10.1148/radiol.2016152893</a></p>
<p><a class="moz-txt-link-freetext" href="https://www.sciencedaily.com/releases/2016/06/160628072028.htm">https://www.sciencedaily.com/releases/2016/06/160628072028.htm</a></p>
<p>By no means a radical improvement, but it is an old rather safe
drug with an amusing side effect (blue pee). <br>
</p>
<blockquote type="cite"><span style="color: rgb(0, 0, 0);
font-family: Arial, sans-serif; font-size: 12px; font-style:
normal; font-variant: normal; font-weight: normal;
letter-spacing: normal; line-height: 21px; orphans: auto;
text-align: left; text-indent: 0px; text-transform: none;
white-space: normal; widows: 1; word-spacing: 0px;
-webkit-text-stroke-width: 0px; display: inline !important;
float: none; background-color: rgb(255, 255, 255);">Methylene
blue is a memory-enhancing drug in animals and humans after a
single dose in the low-dose range of 0.5–4 mg/kg, but it has
opposite effects at doses greater than 10 mg/kg and displays a
hormetic dose response (</span><a data-rid="r15"
data-refrance="15. Bruchey AK, Gonzalez-Lima F. Behavioral,
physiological and biochemical hormetic responses to the
autoxidizable dye methylene blue. Am J Pharmacol Toxicol
2008;3(1):72–79." data-reflink="_i30"
href="http://pubs.rsna.org/doi/10.1148/radiol.2016152893#"
class="ref showRefEvent" style="color: rgb(0, 0, 0);
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white-space: normal; widows: 1; word-spacing: 0px;
-webkit-text-stroke-width: 0px; background-color: rgb(255, 255,
255);">15</a><span style="color: rgb(0, 0, 0); font-family:
Arial, sans-serif; font-size: 12px; font-style: normal;
font-variant: normal; font-weight: normal; letter-spacing:
normal; line-height: 21px; orphans: auto; text-align: left;
text-indent: 0px; text-transform: none; white-space: normal;
widows: 1; word-spacing: 0px; -webkit-text-stroke-width: 0px;
display: inline !important; float: none; background-color:
rgb(255, 255, 255);">).<span class="Apple-converted-space"> <br>
</span></span></blockquote>
<br>
Still, not a good idea to combine with SSRIs,
<a class="moz-txt-link-freetext" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2078225/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2078225/</a><br>
<br>
<pre class="moz-signature" cols="72">--
Dr Anders Sandberg
Future of Humanity Institute
Oxford Martin School
Oxford University
</pre>
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