<div dir="ltr"><div class="gmail_default" style="font-family:comic sans ms,sans-serif;font-size:small;color:#000000">Is the protection against tuberculosis active where there is heterzygosticity, or only when the person has two copies and thus Tay Sachs? I guess the same question pertains to sickle cell anemia and malaria. Anybody know?</div><div class="gmail_default" style="font-family:comic sans ms,sans-serif;font-size:small;color:#000000"><br></div><div class="gmail_default" style="font-family:comic sans ms,sans-serif;font-size:small;color:#000000">bill w</div></div><div class="gmail_extra"><br><div class="gmail_quote">On Wed, Oct 12, 2016 at 3:52 PM, spike <span dir="ltr"><<a href="mailto:spike66@att.net" target="_blank">spike66@att.net</a>></span> wrote:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><span class=""><br>
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-----Original Message-----<br>
From: extropy-chat [mailto:<a href="mailto:extropy-chat-bounces@lists.extropy.org">extropy-chat-bounces@<wbr>lists.extropy.org</a>] On Behalf<br>
Of rex<br>
<br>
<br>
There are several terms for it.<br>
<br>
<a href="https://en.wikipedia.org/wiki/Balancing_selection" rel="noreferrer" target="_blank">https://en.wikipedia.org/wiki/<wbr>Balancing_selection</a><br>
<br>
I suspect it's more common than is generally recognized.<br>
<br>
-rex<br>
--<br>
"You do not examine legislation in light of the benefits it will convey if<br>
properly administered, but in light of the wrongs it would do and the harms<br>
it would cause if improperly administered." --Lyndon B. Johnson<br>
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</span>Thanks Rex. You and Stathis identified it as heterozygote advantage. I<br>
thought there was a more specific term for that concept, but this states the<br>
notion:<br>
<br>
<a href="https://en.wikipedia.org/wiki/Heterozygote_advantage" rel="noreferrer" target="_blank">https://en.wikipedia.org/wiki/<wbr>Heterozygote_advantage</a><br>
<br>
OK cool, so if we identify a bunch of these heterozygote advantages, then we<br>
could use CRISPR to induce the mutant copy widely. Then when couples with<br>
the mutation mate, a heterozygous embryo is chosen, then the result is a<br>
healthier population (even though not one which can reproduce haphazardly.)<br>
<span class="HOEnZb"><font color="#888888"><br>
spike<br>
</font></span><div class="HOEnZb"><div class="h5"><br>
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