<html><head><meta http-equiv="content-type" content="text/html; charset=utf-8"></head><body dir="auto"><div>On Sep 26, 2017, at 4:55 PM, Stathis Papaioannou <<a href="mailto:stathisp@gmail.com">stathisp@gmail.com</a>> wrote:</div><blockquote type="cite"><div><div class="gmail_quote"><div dir="auto">On Tue, 26 Sep 2017 at 8:10 pm, William Flynn Wallace <<a href="mailto:foozler83@gmail.com" target="_blank">foozler83@gmail.com</a>> wrote:</div></div></div><div><div><div class="gmail_quote"><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div><div class="gmail_default" style="font-family:arial,helvetica,sans-serif;font-size:small;color:#000000"></div><div class="gmail_default" style="font-family:arial,helvetica,sans-serif;font-size:small;color:#000000">I got off Naproxen (did I post that?) when the People's Pharmacy, which I do trust, posted a scary journal article about nsaids. No osteoprthritis pain came back, apparently because I also have been taking curcumin and boswellia - anti-inflammatories.</div></div></blockquote><div dir="auto"><br></div></div></div></div><div><div><div class="gmail_quote"><div dir="auto">If there are no good systematic studies of these, how do you know that they work and it isn’t just placebo effect, and that they don’t cause some other long term side-effect? If you stopped the naproxen and nothing happened then I suspect if you stopped the curvumin and boswellia (which seem quite a bit more expensive than naproxen on a cursory online search), or replaced them with something else such as green tea, nothing would happen.</div></div></div></div></blockquote><br><div><font color="#000000"><span style="background-color: rgba(255, 255, 255, 0);">There seem to be good studies of curcumin:</span></font></div><div><font color="#000000"><br></font></div><div><font color="#000000"><span style="background-color: rgba(255, 255, 255, 0);"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637808/#!po=9.89848">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637808/#!po=9.89848</a></span></font></div><div><font color="#000000"><span style="background-color: rgba(255, 255, 255, 0);"><br></span></font></div><div><font color="#000000"><span style="background-color: rgba(255, 255, 255, 0);">And boswellia seems to have some studies behind it too -- though not as strong:</span></font></div><div><font color="#000000"><span style="background-color: rgba(255, 255, 255, 0);"><br></span></font></div><div><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992997/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992997/</a></div><div><font color="#000000"><span style="background-color: rgba(255, 255, 255, 0);"><br></span></font></div><div><font color="#000000"><span style="background-color: rgba(255, 255, 255, 0);">(Note that one is a mouse study -- not a human trial.)</span></font></div><div><font color="#000000"><span style="background-color: rgba(255, 255, 255, 0);"><br></span></font></div><div><font color="#000000"><span style="background-color: rgba(255, 255, 255, 0);">Note also that he said he was taking curcumin and boswellia with naproxen -- not that he went off naproxen then waited a while and started taking them. True, he wasn't doing a double blind on himself, but my guess would be that curcumin or boswellia had some non-placebo impact.<br><br></span></font><div style="line-height: normal;"><div style="line-height: normal;"><span style="line-height: 20px; background-color: rgba(255, 255, 255, 0);">Regards,</span></div><div style="line-height: normal;"><span style="line-height: 20px; background-color: rgba(255, 255, 255, 0);"><br></span></div><div><div style="line-height: normal;"><span style="line-height: 20px; background-color: rgba(255, 255, 255, 0);">Dan</span></div><div style="line-height: normal;"><span style="line-height: 20px; background-color: rgba(255, 255, 255, 0);"> Sample my latest Kindle book "Sand Trap":</span></div><div style="line-height: normal;"><font color="#000000" style="background-color: rgba(255, 255, 255, 0);"><a href="http://mybook.to/SandTrap" style="background-color: rgba(255, 255, 255, 0);">http://mybook.to/SandTrap</a></font></div></div><div style="line-height: normal;"><br></div></div></div></body></html>