<div dir="ltr"><p style="box-sizing:border-box;font-family:proxima-nova,sans-serif;font-size:20px;line-height:26px;margin-top:0px;margin-bottom:26px">“The gut microbiome is emerging as a key factor in the aging process… Abnormal shifts in the gut microbiome, however, have been implicated in the pathogenesis of age-related chronic diseases,” <a href="https://www.sciencedirect.com/science/article/pii/S2468501120300146#!" style="box-sizing:border-box;background-color:transparent;color:rgb(237,102,41);text-decoration-line:none">wrote</a> Drs. Minhoo Kim and Berenice Benayoun at the University of Southern California in a previous article (they were not involved in this study).</p><p style="box-sizing:border-box;font-family:proxima-nova,sans-serif;font-size:20px;line-height:26px;margin-top:0px;margin-bottom:26px">The results don’t mean a longevity probiotic is coming soon to a store near you. The team will still need to test whether isoalloLCA and other unique bile acids from centenarians can prolong healthy longevity through additional participants and animal studies.</p><p style="box-sizing:border-box;font-family:proxima-nova,sans-serif;font-size:20px;line-height:26px;margin-top:0px;margin-bottom:26px">“Like many studies that seek to implicate specific microbiome signatures with particular conditions in humans, as yet the work mostly reveals correlations rather than causality,” said Barrett.</p><p style="box-sizing:border-box;font-family:proxima-nova,sans-serif;font-size:20px;line-height:26px;margin-top:0px;margin-bottom:26px">But the study highlights gut bug bile acids as a potential source of health elixirs. “It may be possible to exploit the bile-acid-metabolizing capabilities of the identified bacterial strains to rationally manipulate the pool for health benefits,” the authors said."</p><p style="box-sizing:border-box;font-family:proxima-nova,sans-serif;font-size:20px;line-height:26px;margin-top:0px;margin-bottom:26px"><a href="https://singularityhub.com/2021/08/10/study-of-160-centenarians-points-to-the-gut-as-a-source-of-healthy-longevity/">https://singularityhub.com/2021/08/10/study-of-160-centenarians-points-to-the-gut-as-a-source-of-healthy-longevity/</a><br></p></div>