<div dir="ltr"><div class="gmail_default" style="font-family:comic sans ms,sans-serif;font-size:large;color:#000000">What is exciting to me is that they are on their way to more easily manipulate emotions and other brain states. Think what they would mean for mental health. The antidepressants and tranquilizers we have now are very crude. bill w</div></div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Thu, Mar 17, 2022 at 2:26 PM Will Steinberg via extropy-chat <<a href="mailto:extropy-chat@lists.extropy.org">extropy-chat@lists.extropy.org</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><div dir="ltr">Also perhaps research growing Echinopsis pachanoi/Lophophora williamsii, and also a little monkey told me is is very, very easy to use Uncle Ben's microwaveable rice packets to grow many kinds of mushrooms, from the bold porcini, to the subtle chanterelle, to the freaky-deaky Psilocybe cubensis, which apparently has spores you can order online completely legally, for looking at with your microscope of course, and it would of course be illegal to use those rice packets as starter substrates for said groovy mushrooms. And apparently there is a community here dedicated to growing all the aforementioned legal edible/medicinal mushrooms here: <a href="https://www.reddit.com/r/unclebens/" target="_blank">https://www.reddit.com/r/unclebens/</a> and totally not the kind that will make you realize you and I and the universe are all one conscious being (but also infinite beings). These little animals are saying some crazy stuff!</div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Thu, Mar 17, 2022 at 3:18 PM Will Steinberg <<a href="mailto:steinberg.will@gmail.com" target="_blank">steinberg.will@gmail.com</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><div dir="ltr">In general they would be mostly synthetic or semisynthetic (ergotamine precursor, could use dmt or ephedrine from plants as a precursor, etc) but there are reports of adding psychedelics to the growth substrate of psilocybe mushrooms which may cause them to hydroxylate the 4th position on the indole ring of whatever chem was added. So in theory adding DiPT to the mushroom substrate can produce some 4-HO-DiPT in addition to the already present 4-HO-DMT (psilocin, which becomes O-phosphoryl-psilocin (psilocybin) in the plant so maybe the resultant chem would be O-phosphoryl-4-HO-DiPT?) .<div><br></div><div>As for the theoretical home researcher, a little bird with huge pupils told me it is exceedingly easy and 100% legal to order Psychotria viridis leaf and Banisteriopsis caapi vine from European clearnet sources, and then it would technically be illegal, but very hard to find or prove given use in a closed environment like, say, your house, to brew these into ayahuasca, which could technically be dosed with various ratios of the leaf (DMT) and vine (MAOI) as well as admixture plants, or other DMT/MAOI containing plants like mimosa hostilis/acacia confusa for DMT or syrian rue for harmala alkaloid MAOI, to produce anywhere from a microdose experience to a mild shroom-type experience to a full-blown 12-hour shit-your-pants vision quest experience. But that's just what the bird told me. He also said something about psychedelic and dissociative analog chemicals also being readily available on the clearnet, including ones that are just straight-up prodrugs for LSD and the like, and are bizarrely completely legal, but he was frying pretty hard at that point and was saying some shit about dark matter being consciousness or something. Idk </div></div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Thu, Mar 17, 2022 at 1:06 PM William Flynn Wallace via extropy-chat <<a href="mailto:extropy-chat@lists.extropy.org" target="_blank">extropy-chat@lists.extropy.org</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><div dir="ltr"><div dir="ltr"><div class="gmail_default" style="font-family:"comic sans ms",sans-serif;font-size:large;color:rgb(0,0,0)"><br></div></div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Thu, Mar 17, 2022 at 11:17 AM Will Steinberg via extropy-chat <<a href="mailto:extropy-chat@lists.extropy.org" target="_blank">extropy-chat@lists.extropy.org</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><div dir="ltr">numerous substituted indoles/tryptamines and substituted phenethylamines. 4-AcO-DMT or 2C-B for example </div></blockquote><div><br></div><div class="gmail_default" style="font-family:"comic sans ms",sans-serif;font-size:large;color:rgb(0,0,0)">Thanks! I'll check my local pharmacy! I assume these and most others are synthetic, not naturally derived from plants, mushrooms, etc. Otherwise, where can I get the seeds? bill w</div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Thu, Mar 17, 2022 at 11:39 AM William Flynn Wallace via extropy-chat <<a href="mailto:extropy-chat@lists.extropy.org" target="_blank">extropy-chat@lists.extropy.org</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><div dir="ltr"><div style="font-family:"comic sans ms",sans-serif;font-size:large;color:rgb(0,0,0)"><a href="https://neurosciencenews.com/psychedelics-conscious-awareness-20203/" target="_blank">https://neurosciencenews.com/psychedelics-conscious-awareness-20203/</a><br></div><div style="font-family:"comic sans ms",sans-serif;font-size:large;color:rgb(0,0,0)"><br></div><div style="font-family:"comic sans ms",sans-serif;font-size:large;color:rgb(0,0,0)">Which ones am I missing out on?</div><div style="font-family:"comic sans ms",sans-serif;font-size:large;color:rgb(0,0,0)"><br></div><div style="font-family:"comic sans ms",sans-serif;font-size:large;color:rgb(0,0,0)">bill w</div></div>
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