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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple style='word-wrap:break-word'><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif'><o:p> </o:p></span></p><div style='border:none;border-top:solid #E1E1E1 1.0pt;padding:3.0pt 0in 0in 0in'><p class=MsoNormal><b><span style='font-size:11.0pt;font-family:"Calibri",sans-serif'>From:</span></b><span style='font-size:11.0pt;font-family:"Calibri",sans-serif'> John Clark <johnkclark@gmail.com> <br><b>…</b></span><o:p></o:p></p></div><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><span class=gmaildefault><b><span style='font-size:13.5pt;font-family:"Tahoma",sans-serif'>John look at that list below. If the developers of those medications have no way to make back the cost of development and qualification thru FDA many times over (to cover the risk) investors would not put money in those companies and none of those medications would exist.<o:p></o:p></span></b></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif'><o:p> </o:p></span></p><h3 style='margin-top:0in'><span class=gmaildefault><span style='font-family:"Arial",sans-serif'> </span></span><span style='font-family:"Arial",sans-serif'>Examples of Price Disparities (Estimated Out-of-Pocket / List Price)<o:p></o:p></span></h3><table class=MsoNormalTable border=0 cellpadding=0><thead><tr><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><strong><span style='font-family:"Arial",sans-serif'>Medication</span></strong><span style='font-family:"Arial",sans-serif'><o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><strong><span style='font-family:"Arial",sans-serif'>Common Indication</span></strong><span style='font-family:"Arial",sans-serif'><o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><strong><span style='font-family:"Arial",sans-serif'>U.S. Retail Price (Approx.)</span></strong><span style='font-family:"Arial",sans-serif'><o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><strong><span style='font-family:"Arial",sans-serif'>Canada Retail Price (Approx.)</span></strong><span style='font-family:"Arial",sans-serif'><o:p></o:p></span></p></td></tr></thead><tr><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><b><span style='font-family:"Arial",sans-serif'>Ozempic</span></b><span style='font-family:"Arial",sans-serif'> (Semaglutide)<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>Type 2 Diabetes / Weight Loss<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$950 – $1,000 / month<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$300 – $330 / month<o:p></o:p></span></p></td></tr><tr><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><b><span style='font-family:"Arial",sans-serif'>Eliquis</span></b><span style='font-family:"Arial",sans-serif'> (Apixaban)<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>Blood Thinner / Stroke Prevention<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$550 – $800 / month<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$130 – $150 / month<o:p></o:p></span></p></td></tr><tr><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><b><span style='font-family:"Arial",sans-serif'>Lantus / Humalog</span></b><span style='font-family:"Arial",sans-serif'> (Insulin)<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>Diabetes<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$280 – $350 / vial<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$30 – $45 / vial<o:p></o:p></span></p></td></tr><tr><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><b><span style='font-family:"Arial",sans-serif'>EpiPen</span></b><span style='font-family:"Arial",sans-serif'> (Epinephrine 2-pack)<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>Severe Allergic Reactions<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$550 – $650<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$100 – $150<o:p></o:p></span></p></td></tr><tr><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><b><span style='font-family:"Arial",sans-serif'>Xarelto</span></b><span style='font-family:"Arial",sans-serif'> (Rivaroxaban)<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>Blood Thinner<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$590 / month<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$135 / month<o:p></o:p></span></p></td></tr><tr><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><b><span style='font-family:"Arial",sans-serif'>Advair Diskus</span></b><span style='font-family:"Arial",sans-serif'> (Fluticasone/Salmeterol)<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>Asthma / COPD<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$350 – $400 / inhaler<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$80 – $160 / inhaler<o:p></o:p></span></p></td></tr><tr><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><b><span style='font-family:"Arial",sans-serif'>Januvia</span></b><span style='font-family:"Arial",sans-serif'> (Sitagliptin)<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>Type 2 Diabetes<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$320 / month<o:p></o:p></span></p></td><td style='border:solid #C4C7C5 1.0pt;padding:6.0pt 9.0pt 6.0pt 9.0pt'><p class=MsoNormal><span style='font-family:"Arial",sans-serif'>~$165 /<o:p></o:p></span></p></td></tr></table><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><b><span style='font-size:13.5pt;font-family:"Tahoma",sans-serif'>I don’t use any of those, but I am glad they exist. Are you?<o:p></o:p></span></b></p><p class=MsoNormal><b><span style='font-size:13.5pt;font-family:"Tahoma",sans-serif'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='font-size:13.5pt;font-family:"Tahoma",sans-serif'>spike</span></b><span style='font-size:11.0pt;font-family:"Calibri",sans-serif'><o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><o:p> </o:p></p></div></body></html>