[Paleopsych] BH: Memory Declines Faster in Male Primates
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Mon Apr 11 22:09:58 UTC 2005
Memory Declines Faster in Male Primates
Findings have implications for developing sex-specific treatments for
age-related cognitive decline
2/10/2005 1:38 PM
Men may be more susceptible to age-related memory decline than women,
suggests a new study in nonhuman primates.
Research conducted at the Yerkes National Primate Research Center
of Emory University in Atlanta has found that spatial memory,
responsible for recording environmental and spatial-orientation
information, declines at a greater rate in male nonhuman primates than
Research leaders Agnes Lacreuse and James Herndon conclude that
sex may influence age-related cognitive decline, which has
implications for developing human treatments to prevent age-related
In tasks measuring spatial memory, the researchers saw young male
nonhuman primates outperform females, similar to what's been found in
In older subjects, however, sex differences no longer existed among
aged male and female nonhuman primates, suggesting that spatial
abilities declined at a greater rate in males.
The researchers next aim to determine what contributes to the
differential decline and to conduct imaging studies to examine any
reductions in brain regions involved in spatial memory.
The research is reported in the journal Behavioral Neuroscience.
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