[Paleopsych] BH: Even Two Days Inactivity May Be Unhealthy
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Sun Jan 23 18:20:56 UTC 2005
Even Two Days Inactivity May Be Unhealthy
Lack of exercise appears to quickly decrease insulin sensitivity, a possible
precursor to diabetes
1/19/2005 2:52 PM
As little as two days physical inactivity appears to decrease the
body's efficient use of insulin, a possible precursor to diabetes and
Professor Frank Booth and doctoral student David Kump of the
University of Missouri-Columbia made the discovery by simulating a
sudden drop in activity in rats.
The researchers allowed the rats to run on an exercise wheel for three
weeks and then locked the wheel for two days.
They found that insulin sensitivity decreased the longer the rats
"Everyone is looking at the benefits of exercise, but we are looking
at the consequences of stopping that exercise," says Kump. "People
already know that exercise is good for them. This shows that within a
very short time frame of inactivity, the insulin does not work as well
and might have negative effects."
Decreased insulin sensitivity is thought to put people at greater risk
of such conditions as diabetes, heart disease, obesity and
Insulin moves sugar from the blood into muscles for energy. In people
who are active, this process and the process of turning the sugar into
energy is more efficient. In people who are inactive, less so.
But what about people who are active and then take a break?
The researchers found that, at least in rats, just two days of
inactivity causes the amount of sugar taken into muscles in response
to insulin to be reduced by about a third.
Booth says that the research shows that such changes can occur earlier
The research is reported in the Journal of the Physiological
Society (read abstract).
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