[ExI] Whole-organ cryopreservation successful.
rafal.smigrodzki at gmail.com
Wed Apr 30 00:45:20 UTC 2008
On Mon, Apr 28, 2008 at 8:58 PM, Bret Kulakovich
<bret at bonfireproductions.com> wrote:
> Not to over-simplify, obviously, but this is great news.
> I believe the key word here is "All" rather than "rat"
> Journal of Thoracic and Cardiovascular Surgery
> Successful restoration of function of frozen and thawed isolated rat hearts
> " After normothermic perfusion, cold cardioplegia was induced followed by
> perfusion with a cryoprotecting agent. Hearts were than frozen to –8°C (45 ±
> 8 minutes), thawed, and reperfused (60 minutes).
> Results: All frozen and thawed hearts regained normal electric activity. "
### The problem is that they have shown only recovery of electrical
activity which is of course good but this doesn't tell us too much
about the prospects for a successful transplant. That would only be
proven by recovery of function on reimplantation, and there we could
encounter significant difficulties due to induction of apoptosis.
Still, it's nice work.
More information about the extropy-chat