[ExI] 'Magic mushroom' compound may work just as well as antidepressants, small study finds

Nuala Thomson nuala.t at gmail.com
Sun Apr 18 02:36:49 UTC 2021


I'm so sorry Bill W!
That is a huge question and hard to answer.
No matter what, every single person reacts differently and experiences
differently to both pharmaceuticals and illegal drugs. So the latest in DNA
testing to narrow down which antidepressants are more likely to help rather
than hinder I think is a very much needed first step.
https://www.health.harvard.edu/blog/gene-testing-to-guide-antidepressant-treatment-has-its-time-arrived-2019100917964
The next stage is going to be able to confirm whether it's a person's state
of mind/way of thinking or an actual chemical imbalance and therefore
whether a form of therapy (CBT, DBT, etc.) Would be better suited to them
over antidepressants, stabilisers, or antipsychotics. The struggle to
differentiate on the more suitable path is real, and quite often here
(Australia) doctors opt for both (therapy and drugs) simultaneously. This
is both good and bad.
I'm going to go back to gene testing for antidepressants for a moment and
I'm going to use 'Subject J' as an example. He had been on and off
antidepressants for the better part of 20 years trying to find one that
actually worked with acceptable side effects. I can't say what the last one
he took was but I can say that it was 'the one'. His neuro chemistry is
permanently changed and he no longer needs to take medication. This is what
I hope the dna tests will help to accomplish in a more acceptable time
frame.
I could talk a lot more on the use of therapy treating borderline and
bipolar disorders which stem from trauma but I want to touch on illicit
substances.
Again, everyone reacts differently so one person might respond to MDMA as I
would expect (loving, friendly, talkative, open communication) another
person will respond entirely differently. An example that I saw was
nauseous, tired, completely closed off. That person ended up just going to
sleep. Opposite responses will happen with everything.
Illicit drugs and mental illness is also a mega topic for me and typing
this email on a phone screen is getting frustrating.
Illicit substances in the use for dealing with mental illness is not as
funded as I would like it to be, and obviously this email started with
evidence that it should have more funding. MDMA in couples or marriage
sessions can be great as it is the love drug. People are able to openly
communicate coming from a place of love instead of a place of spite or
maliciousness. Hallucinogenics I'm assuming everyone knows how they work
whether or not you've actually tried any. I believe for a more permanent
response in the treatment of mental illness the trip should be guided. I'm
going to refer to my own experiences for this one. My first time ever
specifically. I was 18 and dating a pretty amazing person. I also have a
history of mental illness myself. Keeping this simple and vague; Somewhere
in the journey, in the span of about 30min I cycled through every possible
emotion processing childhood abuse. The person I was with just allowed and
accepted everything and listened.
Now for sure there is still some processing to do but not like that. That
was about 75% of the process complete in one go. If I had been alone in
that, it would not have gone like that. Long term, the benefits still blow
my mind.
It's that benefit that I hope will eventually be more accepted. Micro
dosing is certainly a lot safer and more easily controlled.
A major problem I see with mental illness and illicit drugs is the habitual
use as a way of masking pain and trauma. The excessive use stops the
healing process and causes more long term issues. I've found the people in
this situation are a lot less likely to seek professional help, are
reluctant to let someone help them, and will just continue until something
changes, but denial runs strong in that group.
And then we have the group of people (such as myself) who have pre-existing
mental illness, who micro dosing would be extremely beneficial for, but
where the risk of adverse effects is strong.
E.g.. Paranoid after effects.

I'm sorry. I would love to continue but I'm truly sick of typing on a
phone. I would love your opinion and experiences on such topics and we can
continue the conversation later.

On Sun., Apr. 18, 2021, 09:17 William Flynn Wallace via extropy-chat, <
extropy-chat at lists.extropy.org> wrote:

>
>
> On Fri, Apr 16, 2021 at 8:16 PM Nuala Thomson via extropy-chat <
> extropy-chat at lists.extropy.org> wrote:
>
>> Will, do you mean pharmaceuticals in terms of the treatment of mental
>> illness or something else?
>>
>
> It's Bill W - anything at all that you know - mental illness -
> self-treatment for mental problems, etc.  Just the illegal drugs.   bill w
>
>>
>> On Sat., Apr. 17, 2021, 10:40 William Flynn Wallace via extropy-chat, <
>> extropy-chat at lists.extropy.org> wrote:
>>
>>> Nuala, what do you think of the efficacy of the drugs as far as you are
>>> concerned?   bill w
>>>
>>> On Fri, Apr 16, 2021 at 7:30 PM Nuala Thomson via extropy-chat <
>>> extropy-chat at lists.extropy.org> wrote:
>>>
>>>> Here in Aus medical marijuana still has THC and gets you fucked up! The
>>>> strongest weed you could possibly get.
>>>> On the other hand CBD oil which is also being shown to help with
>>>> anxiety and depression does not contain THC.
>>>>
>>>> On Sat., Apr. 17, 2021, 04:00 William Flynn Wallace via extropy-chat, <
>>>> extropy-chat at lists.extropy.org> wrote:
>>>>
>>>>> Yes, but medical marijuana has the THC taken out of it - no highs.
>>>>>>
>>>>>
>>>>> This is false  It depends:
>>>>>
>>>>>
>>>>> https://www.mayoclinic.org/healthy-lifestyle/consumer-health/in-depth/medical-marijuana/art-20137855#:~:text=Medical%20marijuana%20%E2%80%94%20also%20called%20medical,)%20and%20CBD%20(cannabidiol
>>>>> ).
>>>>>
>>>>> On Fri, Apr 16, 2021 at 11:37 AM Will Steinberg via extropy-chat <
>>>>> extropy-chat at lists.extropy.org> wrote:
>>>>>
>>>>>>
>>>>>>
>>>>>> On Fri, Apr 16, 2021, 12:09 PM William Flynn Wallace via extropy-chat
>>>>>> <extropy-chat at lists.extropy.org> wrote:
>>>>>>
>>>>>>> Yes, but medical marijuana has the THC taken out of it - no highs.
>>>>>>>
>>>>>>
>>>>>> This is false
>>>>>>
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