[extropy-chat] Re:Resuscitation: and Armchair Cryonicists-hypothermic liferaft

[Extropian Agroforestry Ventures Inc.]

The concept goes thusly:
The liferaft =
-sleeping /body bag like sack made so that no 2 arms or legs touch each 
other or body
-zipper + ziplock seal
- control/RFID biomonitor keypad with on outside
-stage 1- evacuate liner to ensure good skin contact with sack
-person put inside without outer clothes , shoes etc
-put cooling hood or cap over all of head less face, face cover ziplock 
cover after body cooled off
-start in 2 parts; activation of emergency cooling packs layer of sack 
to quick cool body; hood cooling cycle
co2 based for higher cooling rate
-infusion of adjuvants may include:
Caffeinol as neuroprotectant; berberine in DMSO solution as 
neuroprotectant; cannabidiol in DMSO solution as neuroprotectant
-optional defib cycle to pump neuroprotectants into cooling  body uniformly

The adjuvants are designed to allow the brain to survive a longer 
cool-off time than the usual 3-5 minutes.
as well as allow for easier re-start of body by hospital medical team
-once body temp is near 32F optional external hookups to maintain cooled 
body during extended transport

Once the working prototype is designed and tested  , the actual mfg 
costs may be quite reasonable

Morris Johnson

Hara Ra wrote:

> To posts by Eugen and Kevin.
>
> For Kevin:
>
>     My (very limited) information on ischemia is that the Krebs cycle 
> is vulnerable to the loss of oxygen. (The machinery for this cycle is 
> passed via the egg, so evolution in mammalia long ago lost any 
> protection if it was there.) When O2 is returned to the cell, the 
> Krebs cycle has failed, and some steps lack the needed intermediate 
> products, the result is a toxic accumulation of reactive radicals and 
> serious irreparable damage.
>
>     I don't know about what the arteries do, but failure of their 
> Krebs cycle may well do as you describe.
>
> For Eugen:
>
>     Thanks for taking my point and clarifying it. If you read my sig 
> file, I don't think I am an "Armchair cryonicist". Please correct me 
> if you think so, and explain why.
>
> For Both:
>
>     If the law permitted touching the patienr prior to announcement of 
> death (not likely in the USA for a very long time), then, in a clinic, 
> 1) give patient general anesthesia 2) cannulate femorals 3) pump in 
> intermediate cooldown fluid (plasma blood extender) with high 
> oxygenation. As the body temp cools, the heart stops at about 50 deg 
> F. Cooldown to 0 deg C can be done in about 10 minutes, without 
> subjecting the patient to ischemia.
>
>     But, folks, this is legally MURDER, and dat's how it is in the 
> good ole USA. :(
>
> PS We currently do no longer use the Thumper, which is an obscene 
> bastard of equipment fully capable of major injury to both patient and 
> rescue team. Respiratory support is no longer in the protocol, because 
> basically all patients are over the 4 minute limit, and restoring O2 
> is a bad idea. We use an Ambi product, a suction cup with handles, to 
> maintain circulation for the 3-5 minutes it takes to circulate the 
> medicines (a proprietary cocktail of anticoaguants, clot busters and 
> other stuff)
> ==================================
> =   Hara Ra (aka Gregory Yob)    =
> =     harara at sbcglobal.net       =
> =   Alcor North Cryomanagement   =
> =   Alcor Advisor to Board       =
> =       831 429 8637             =
> ==================================
>
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