[ExI] good bexarotene article
avantguardian2020 at yahoo.com
Sun Feb 12 06:09:07 UTC 2012
----- Original Message -----
> From: spike <spike66 at att.net>
> To: 'ExI chat list' <extropy-chat at lists.extropy.org>
> Sent: Saturday, February 11, 2012 10:41 AM
> Subject: Re: [ExI] good bexarotene article
>> ... On Behalf Of Jeff Davis
>> ...Best outcome: an effective off-label (ie non-FDA "owned")
> therapy that becomes the champion example for patients' rights. Best, Jeff
> Ja well said. Yesterday we made some calls, learned that it is generally OK
> for a GP to prescribe off-label at the doctor's discretion. We have a
> message in to our family member's doctor asking if she is willing to
> prescribe bexarotene off-label, or do we need to go find a doctor who will.
> The next thing we need is to calculate or estimate the dosage. For a first
> shot, I am trying to find out what dose they gave the mice, then scale it up
> linearly. Would you estimate a mouse is about 50 to 60 grams? So whatever
> the mice received, scale it up by a factor of about 1000?
> The medications which contain bexarotene supply the information of the
> concentration of the active ingredient, so it will be an easy calculation.
> Open to suggestion here. The topic is temporarily open season, so your
> suggestion is free and welcome.
Does anybody have an institutional Science subscription that could send me a copy of this article?
The dosing information and administration route are probably in there.
"When the going gets weird, the weird turn pro." - Hunter S. Thompson
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