[ExI] Living longer - Genes?

[William Flynn Wallace]

On Sat, Dec 19, 2015 at 3:20 AM, BillK <pharos at gmail.com> wrote:

> In the search for extending lifespan geneticists have been searching
> for genes that protect against the effects of ageing, but with little
> success so far.
> Another suggestion is that perhaps centenarians don't have anti-ageing
> genes, but do have disease-protecting genes. i.e. they live longer
> because they get fewer diseases.
> New research is pointing in this direction.
>
> <http://time.com/4153835/live-longer-genetic-clues/>
> Quotes:
> How to Live to 100: Researchers Find New Genetic Clues
> Alice Park    Dec. 17, 2015
>
> In a new analysis, researchers explore whether people live longer
> because they avoid disease or because they possess some anti-aging
> secret.
> But in a paper published in PLOS Genetics, researchers led by Stuart
> Kim, professor of developmental biology and genetics at Stanford
> University, questions that dogma. He found that on the contrary,
> centenarians may have fewer of the genes that contribute to major
> chronic diseases. That doesn’t mean that people who live to their 100s
> also don’t possess some protective anti-aging genes as well, but Kim’s
> study shows that they don’t experience as much disease as people who
> are shorter-lived.
>
> Kim’s team shows that the way centenarians reach their second century
> may involve more than just being blessed with anti-aging genes. “We
> found that, at least in part, they live longer because they don’t get
> sick,” he says.
> -------
>
>
> BillK
> ​What I think is going to happen:  epigenetic research will find that what
> your mother and father and even grandmothers and grandfathers ate, smoked,
> etc.  will have turned on or off certain genes​ that affect the immune
> system and perhaps other things that affect aging.  Isn't it kind of scary
> that what you do can affect your grandchildren?  (before having children,
> of course) -  (am currently reading Nessa Carey's 'The Epigenetics
> Revolution')
>
> ​bill w​


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