[ExI] First hint that body’s ‘biological age’ can be reversed

[John Clark]

The study was conducted by cryobiologist Dr. Gregory Fahy and involved
Human Growth Hormone and two common diabetes drugs, dehydroepiandrosterone
(DHEA) and metformin. The results are interesting because it didn't just
slow down the biological clock it reversed it, but it may not be rock solid
because the clinical study was small ( just 9 white men between 51 and 65)
and it did not contain a control. The discovery was an accident, the drug
trial was set up to see if growth hormone could be safely used to restore
the thymus gland and anti-diabetic drugs were only included because growth
hormone can cause diabetes. After the trial was over they found that in 7
of the 9 men the thymus was restored, and then as an afterthought Fahy
checked on their epigenetic clock and got a surprise.

It seems to me the next step should be to try this drug cocktail in mice
and see if they live longer.

Drugs seemed to rejuvenate the body’s ‘epigenetic clock
<https://www.nature.com/articles/d41586-019-02638-w?utm_source=Nature+Briefing&utm_campaign=eae3387943-briefing-dy-20190906&utm_medium=email&utm_term=0_c9dfd39373-eae3387943-44221073>

John K Clark
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