[ExI] First hint that body’s ‘biological age’ can be reversed

Max More max at maxmore.com
Mon Sep 9 00:35:39 UTC 2019


You should be able to get the paper here:


https://drive.google.com/file/d/0B97CJJ5YOfctalRfZExnd2lHUmRyYUNWMFZYMUgzSXJKVzg4/view


--Max (Subject #1)

On Fri, Sep 6, 2019 at 1:07 PM John Clark via extropy-chat <
extropy-chat at lists.extropy.org> wrote:

> The study was conducted by cryobiologist Dr. Gregory Fahy and involved
> Human Growth Hormone and two common diabetes drugs, dehydroepiandrosterone
> (DHEA) and metformin. The results are interesting because it didn't just
> slow down the biological clock it reversed it, but it may not be rock solid
> because the clinical study was small ( just 9 white men between 51 and 65)
> and it did not contain a control. The discovery was an accident, the drug
> trial was set up to see if growth hormone could be safely used to restore
> the thymus gland and anti-diabetic drugs were only included because
> growth hormone can cause diabetes. After the trial was over they found that
> in 7 of the 9 men the thymus was restored, and then as an afterthought
> Fahy checked on their epigenetic clock and got a surprise.
>
> It seems to me the next step should be to try this drug cocktail in mice
> and see if they live longer.
>
> Drugs seemed to rejuvenate the body’s ‘epigenetic clock
> <https://www.nature.com/articles/d41586-019-02638-w?utm_source=Nature+Briefing&utm_campaign=eae3387943-briefing-dy-20190906&utm_medium=email&utm_term=0_c9dfd39373-eae3387943-44221073>
>
> John K Clark
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> extropy-chat mailing list
> extropy-chat at lists.extropy.org
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>


-- 

Max More, PhD
Strategic Philosopher
Co-editor, *The Transhumanist Reader*
http://www.amazon.com/Transhumanist-Reader-Contemporary-Technology-Philosophy/dp/1118334310/ref=sr_1_1?s=books&ie=UTF8&qid=1372225570&sr=1-1&keywords=the+transhumanist+reader
President & CEO, Alcor Life Extension Foundation
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