[ExI] Dope was Re: state of conflict technology

William Flynn Wallace foozler83 at gmail.com
Sun Jan 12 16:38:18 UTC 2020

to allow low fitness alleles to be eliminated by natural selection.  rafal

But as you know more than most, we have thousands of diseases or conditions
with some genetic links that we have had for many millennia and they are
still around.  Just waiting for natural selection seems a poor choice.  I
can see a future where everyone will get genetic testing, paid for in part
by the government, since health conditions of children drain a lot of
public funds.  Prevention is always better.  Of course there will be those
who resist such testing and they will be shown that they are paying the
price by the poorer health of their children compared to those tested.

bill w

On Sat, Jan 11, 2020 at 7:28 PM Rafal Smigrodzki via extropy-chat <
extropy-chat at lists.extropy.org> wrote:

> On Sat, Jan 11, 2020 at 11:59 AM Keith Henson via extropy-chat <
> extropy-chat at lists.extropy.org> wrote:
> Rafal Smigrodzki <rafal.smigrodzki at gmail.com> wrote:
> > Low fitness should lead to elimination of
>> the responsible alleles. Keeping deleterious alleles artificially
>> protected
>> from extinction only adds to misery. Deleterious alleles have a cost to
>> the
>> filial generation and a cost to non-carriers, a cost paid in
>> perpetuity when evolution is thwarted.
>> What you say is true.  It's also a really bad path to take.
> ### Why?
>> Fortunately, we stand on the edge of taking control of our DNA.  It
>> will be possible to eliminate the deleterious alleles in one
>> generation, a huge improvement over discovering that the kid you
>> raised at great effort and cost has serious genetic problems and
>> should not have children.
> ### Yes, absolutely! But please note, to eliminate the deleterious alleles
> by genetic engineering there has to be a force, an influence of some sort,
> that would incentivise parents/society/government/everybody to actually
> implement the process. How is that going to happen unless the social cost
> of deleterious alleles is somehow allowed to influence behavior? Without
> incentives hardly anything happens. Somebody needs to feel the sting of
> making the wrong decision, like giving your child deleterious genes through
> negligence or intent, to be persuaded to make the right decision. In terms
> of incentives this is not that much different from what I suggested above,
> to allow low fitness alleles to be eliminated by natural selection.
> Rafal
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