[ExI] A Secret to Healthy Aging May Be the Bugs in Your Microbiome

[John Grigg]

“The gut microbiome is emerging as a key factor in the aging process…
Abnormal shifts in the gut microbiome, however, have been implicated in the
pathogenesis of age-related chronic diseases,” wrote
<https://www.sciencedirect.com/science/article/pii/S2468501120300146#!> Drs.
Minhoo Kim and Berenice Benayoun at the University of Southern California
in a previous article (they were not involved in this study).

The results don’t mean a longevity probiotic is coming soon to a store near
you. The team will still need to test whether isoalloLCA and other unique
bile acids from centenarians can prolong healthy longevity through
additional participants and animal studies.

“Like many studies that seek to implicate specific microbiome signatures
with particular conditions in humans, as yet the work mostly reveals
correlations rather than causality,” said Barrett.

But the study highlights gut bug bile acids as a potential source of health
elixirs. “It may be possible to exploit the bile-acid-metabolizing
capabilities of the identified bacterial strains to rationally manipulate
the pool for health benefits,” the authors said."

https://singularityhub.com/2021/08/10/study-of-160-centenarians-points-to-the-gut-as-a-source-of-healthy-longevity/
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