[ExI] uv as an antiviral

[Stathis Papaioannou]

On Sat, 12 Nov 2022 at 16:00, spike jones via extropy-chat <
extropy-chat at lists.extropy.org> wrote:

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> *From:* extropy-chat <extropy-chat-bounces at lists.extropy.org> *On Behalf
> Of *Stathis Papaioannou via extropy-chat
> *Subject:* Re: [ExI] uv as an antiviral
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> On Sat, 12 Nov 2022 at 07:27, spike jones via extropy-chat <
> extropy-chat at lists.extropy.org> wrote:
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> From: spike at rainier66.com <spike at rainier66.com>
> Subject: uv as an antiviral
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> >>>...BillK, regarding that UV light business... that's why we call it
> research, rather than refind.  spike
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> >>…BillK my apologies for belaboring this point, but I had a new wacky
> idea.
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> >>…Recall that when the mRNA vaccines became available in 2020, other
> wacky lines of research were abandoned.  We had the vaccine, hooray!  But
> then...we found out …
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> >…Why couldn't they just fix it without all the mucking around? Why not
> sack them all and put competent people in their place?
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> Stathis Papaioannou
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> Stathis I have a notion that when a technique was discovered to make
> generate mRNA, the whole idea was just so damn sexy we could scarcely help
> being seduced by it.  It sure looked to me like if we could defeat one
> virus that way, we could defeat all of them the same way.  A new strain of
> flu comes along every season.  We grab it as soon as the first cases show
> up, read the RNA, synthesize a bunch of it, poke it in everybody’s arm, no
> flu season that year.  Then once we get that one, down goes chicken pox,
> measles, shingles, herpes, ebola, AIDS becomes an unpleasant memory, the
> common cold becomes the uncommon cold because it is seldom seen.
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> Would not we be the new Jonas Salk?  The modern Alexander Fleming?  We
> were the generation who finally made the big breakthrough.  Sure, let’s
> have a huge victory party celebrating how awesome we are.  But then…
> oopsies, reality messed up everything.  The immune system didn’t seem to
> know or care there is a vaccine here to offer it training.  It didn’t get
> any better at making the right T cells.  But sure, the immune system is
> willing, eager to hand over that task of fighting covid if we are ready to
> take it over.  And if we do, it doesn’t want its former job back.
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> There was nothing wrong with the people.  We were collectively seduced by
> a sexy idea, but wasn’t quite right.  The history of science is filled with
> similar examples.
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> I haven’t given up on getting an mRNA vaccine which does train the immune
> system.  It was elation followed by disappointment, but overall good has
> come of it.  We all learned so much about immunology, learned a lot about
> civics, learned a lotta about a lotta.
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Both vaccination and infection result in a relatively long-lasting T cell
response. But if it didn’t, it didn’t. A lot that we do in medicine is only
marginally effective. Vaccines in general are historically by far the
single most effective medical intervention in history, if we exclude such
things as improved sanitation.

https://www.nature.com/articles/s41590-022-01175-5

-- 
Stathis Papaioannou
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