[ExI] There's already a vaccine for heart disease!

[Jason Resch]

This is the problem with retrospective studies. They don't consider or
don't properly account for any number of confounding factors, such as the
healthy vaccine effect, the compliers effect, or the fact that people near
death often aren't given vaccines.

We know that last year's flu vaccine had negative efficacy (those who
received it were more 26.9% likely to get the flu), so by what proposed
biological mechanism could such an injection explain a reduction in heart
disease? To me the most plausible answer is that it is a combination of one
or more confounding factors, and it is premature to conclude the
flu vaccine actually confers any reduction to heart disease.

This becomes more clear when you look at all causes of mortality, and you
will likely see a reduction in cancer deaths, automobile deaths, Alzheimer
deaths, etc. and it will seem like you have found a miracle medicine that
is suitable for every disease and ailment known to man. But it is an
illusion of the biases inherent to observational studies that lack
randomized controls.

Jason


On Mon, Dec 22, 2025 at 7:08 AM John Clark via extropy-chat <
extropy-chat at lists.extropy.org> wrote:

> *The following is from the December 17, 2025 issue of the journal Nature: *
>
> *"A study of 9,000 adults found that those who received the flu shot were
> 34% less likely to experience serious cardiovascular events in the next
> year than were those who did not receive the vaccine.  For people with
> recent cardiac issues, the benefits were even more pronounced, with a 45%
> lower risk of a serious event.[...] Clinicians should make it clear that
> for individuals who are at elevated risk of cardiovascular disease, the flu
> vaccine isn’t just a ‘nice to have’ — it’s a clinical necessity."*
>
> *There's already a vaccine for heart disease*
> <https://www.nature.com/articles/d41586-025-03598-0?utm_source=Live+Audience&utm_campaign=82ce72787e-nature-briefing-daily-20251218&utm_medium=email&utm_term=0_-33f35e09ea-50169436>
>
> *John K Clark    See what's on my new list at  Extropolis
> <https://groups.google.com/g/extropolis>*
> lxg
>
>
>
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>
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