[extropy-chat] Question for Rafal was Alternative to Cryo

[The Avantguardian]

Hi Rafal. I am glad you have started posting again.
Since you are the list expert on mitochondria, I am
very curious as to your opinion on Blackstone et al.'s
recent proof of principle that reversible electron
transport chain inhibitors could be used to slow down
metabolism, and thus aging through ROS, by inducing a
hibernation-like state of suspended animation. The
article in question is here:

http://www.sciencemag.org/cgi/content/full/308/5721/518

The question I have is could this theoretically allow
the elderly or the terminally ill to survive the
several decades for SENS and other medical
advancements to come up with cures for their
conditions? Could this be a viable alternative to
cryogenic suspension? Also there is much controversy
in the literature regarding the neurotoxic effects of
the hydrogen sulphide (H2S) gas that Blackstone uses
to induce this condition in mice. Do you know of any
other reversible inhibitors of cytochrome c or the
other components of the ETC that could serve the same
purpose with less toxicity?    

The Avantguardian 
is 
Stuart LaForge
alt email: stuart"AT"ucla.edu

"I don't want to achieve immortality through my work. I want to achieve it through not dying." - Woody Allen

"Our hope of immortality does not come from any religions, but nearly all religions come from that hope" - Robert G. Ingersoll


		
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