[ExI] another step towards uploading

Rafal Smigrodzki rafal.smigrodzki at gmail.com
Wed Oct 2 04:05:16 UTC 2013

Coming just weeks after description of helium persufflation for
fracture-free cryonic suspension, here is this:


This is enormously interesting. 10 nm resolution for MRI, if coupled
to MRS (MR spectroscopy) could lead to developing the ability to read
off synaptic strengths directly from frozen tissue. This would be a
major improvement over currently envisioned techniques, such as
antibody perfusion or other molecule-specific staining techniques,
followed by near-field microscopy. Staining is notoriously difficult
and variable and perfusion of frozen tissue is essentially impossible.

A technique capable of directly reading nanoscale molecular
distributions of multiple molecular species (a prerequisite for
individual brain physiology reconstruction) is the holy grail of brain
uploading. Near-field MRS could be it, perhaps.


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