[ExI] Longevity Day and Longevity Month - October 2016

Anders anders at aleph.se
Sat Jul 9 11:33:53 UTC 2016

On 2016-07-09 11:06, BillK wrote:
> Objective tests are required and for life extension in humans the 
> onlyreal test is living longer. And even that may be an individual 
> exceptional case.

Liz Parrish is AFAIK doing well; at least measurable improvements in 
muscle mass and longer telomeres. But in her case much of the concern 
might be more about the safety of her gene therapy than the efficacy.

Individual variability is an interesting issue. We know for cognitive 
enhancement that variability is big because you need to fit the 
enhancement with the cognitive task and cognitive style to get the 
biggest effect (largely due to individual pharmacological responses and 
where the cognitive bottlenecks are). I am more uncertain about the 
variability in ageing, but my impression is that there are both standard 
problems that presumably can be fixed in roughly the same way and some 
idiosyncratic ageing effects that may require individualized therapy; 
that will be tricky to research and optimize.

On Monday I will become 2*2*11, so I have started paying attention more 
to actionable, well-supported and higher effect-sized interventions. But 
I think we may need to come up with better ways of investigating and 
testing them.

Dr Anders Sandberg
Future of Humanity Institute
Oxford Martin School
Oxford University

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