[ExI] 'Magic mushroom' compound may work just as well as antidepressants, small study finds

Sun Apr 18 03:52:17 UTC 2021

 Nuala Thomson, I look forward to hearing further what you have to say... I
find these subjects deeply fascinating....

John

On Sun, Apr 18, 2021 at 10:40 AM Nuala Thomson via extropy-chat <
extropy-chat at lists.extropy.org> wrote:

> I'm so sorry Bill W!
> That is a huge question and hard to answer.
> No matter what, every single person reacts differently and experiences
> differently to both pharmaceuticals and illegal drugs. So the latest in DNA
> testing to narrow down which antidepressants are more likely to help rather
> than hinder I think is a very much needed first step.
>
> https://www.health.harvard.edu/blog/gene-testing-to-guide-antidepressant-treatment-has-its-time-arrived-2019100917964
> The next stage is going to be able to confirm whether it's a person's
> state of mind/way of thinking or an actual chemical imbalance and therefore
> whether a form of therapy (CBT, DBT, etc.) Would be better suited to them
> over antidepressants, stabilisers, or antipsychotics. The struggle to
> differentiate on the more suitable path is real, and quite often here
> (Australia) doctors opt for both (therapy and drugs) simultaneously. This
> is both good and bad.
> I'm going to go back to gene testing for antidepressants for a moment and
> I'm going to use 'Subject J' as an example. He had been on and off
> antidepressants for the better part of 20 years trying to find one that
> actually worked with acceptable side effects. I can't say what the last one
> he took was but I can say that it was 'the one'. His neuro chemistry is
> permanently changed and he no longer needs to take medication. This is what
> I hope the dna tests will help to accomplish in a more acceptable time
> frame.
> I could talk a lot more on the use of therapy treating borderline and
> bipolar disorders which stem from trauma but I want to touch on illicit
> substances.
> Again, everyone reacts differently so one person might respond to MDMA as
> I would expect (loving, friendly, talkative, open communication) another
> person will respond entirely differently. An example that I saw was
> nauseous, tired, completely closed off. That person ended up just going to
> sleep. Opposite responses will happen with everything.
> Illicit drugs and mental illness is also a mega topic for me and typing
> this email on a phone screen is getting frustrating.
> Illicit substances in the use for dealing with mental illness is not as
> funded as I would like it to be, and obviously this email started with
> evidence that it should have more funding. MDMA in couples or marriage
> sessions can be great as it is the love drug. People are able to openly
> communicate coming from a place of love instead of a place of spite or
> maliciousness. Hallucinogenics I'm assuming everyone knows how they work
> whether or not you've actually tried any. I believe for a more permanent
> response in the treatment of mental illness the trip should be guided. I'm
> going to refer to my own experiences for this one. My first time ever
> specifically. I was 18 and dating a pretty amazing person. I also have a
> history of mental illness myself. Keeping this simple and vague; Somewhere
> in the journey, in the span of about 30min I cycled through every possible
> emotion processing childhood abuse. The person I was with just allowed and
> accepted everything and listened.
> Now for sure there is still some processing to do but not like that. That
> was about 75% of the process complete in one go. If I had been alone in
> that, it would not have gone like that. Long term, the benefits still blow
> my mind.
> It's that benefit that I hope will eventually be more accepted. Micro
> dosing is certainly a lot safer and more easily controlled.
> A major problem I see with mental illness and illicit drugs is the
> habitual use as a way of masking pain and trauma. The excessive use stops
> the healing process and causes more long term issues. I've found the people
> in this situation are a lot less likely to seek professional help, are
> reluctant to let someone help them, and will just continue until something
> changes, but denial runs strong in that group.
> And then we have the group of people (such as myself) who have
> pre-existing mental illness, who micro dosing would be extremely beneficial
> for, but where the risk of adverse effects is strong.
> E.g.. Paranoid after effects.
>
> I'm sorry. I would love to continue but I'm truly sick of typing on a
> phone. I would love your opinion and experiences on such topics and we can
> continue the conversation later.
>
> On Sun., Apr. 18, 2021, 09:17 William Flynn Wallace via extropy-chat, <
> extropy-chat at lists.extropy.org> wrote:
>
>>
>>
>> On Fri, Apr 16, 2021 at 8:16 PM Nuala Thomson via extropy-chat <
>> extropy-chat at lists.extropy.org> wrote:
>>
>>> Will, do you mean pharmaceuticals in terms of the treatment of mental
>>> illness or something else?
>>>
>>
>> It's Bill W - anything at all that you know - mental illness -
>> self-treatment for mental problems, etc.  Just the illegal drugs.   bill w
>>
>>>
>>> On Sat., Apr. 17, 2021, 10:40 William Flynn Wallace via extropy-chat, <
>>> extropy-chat at lists.extropy.org> wrote:
>>>
>>>> Nuala, what do you think of the efficacy of the drugs as far as you are
>>>> concerned?   bill w
>>>>
>>>> On Fri, Apr 16, 2021 at 7:30 PM Nuala Thomson via extropy-chat <
>>>> extropy-chat at lists.extropy.org> wrote:
>>>>
>>>>> Here in Aus medical marijuana still has THC and gets you fucked up!
>>>>> The strongest weed you could possibly get.
>>>>> On the other hand CBD oil which is also being shown to help with
>>>>> anxiety and depression does not contain THC.
>>>>>
>>>>> On Sat., Apr. 17, 2021, 04:00 William Flynn Wallace via extropy-chat, <
>>>>> extropy-chat at lists.extropy.org> wrote:
>>>>>
>>>>>> Yes, but medical marijuana has the THC taken out of it - no highs.
>>>>>>>
>>>>>>
>>>>>> This is false  It depends:
>>>>>>
>>>>>>
>>>>>> https://www.mayoclinic.org/healthy-lifestyle/consumer-health/in-depth/medical-marijuana/art-20137855#:~:text=Medical%20marijuana%20%E2%80%94%20also%20called%20medical,)%20and%20CBD%20(cannabidiol
>>>>>> ).
>>>>>>
>>>>>> On Fri, Apr 16, 2021 at 11:37 AM Will Steinberg via extropy-chat <
>>>>>> extropy-chat at lists.extropy.org> wrote:
>>>>>>
>>>>>>>
>>>>>>>
>>>>>>> On Fri, Apr 16, 2021, 12:09 PM William Flynn Wallace via
>>>>>>> extropy-chat <extropy-chat at lists.extropy.org> wrote:
>>>>>>>
>>>>>>>> Yes, but medical marijuana has the THC taken out of it - no highs.
>>>>>>>>
>>>>>>>
>>>>>>> This is false
>>>>>>>
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