[ExI] lipoprotein(a)

[William Flynn Wallace]

Hmm.  I read where niacin in some form is used on the lipoprotein.  bill w

On Thu, Mar 3, 2022 at 11:55 AM BillK via extropy-chat <
extropy-chat at lists.extropy.org> wrote:

> On Thu, 3 Mar 2022 at 00:38, William Flynn Wallace via extropy-chat
> <extropy-chat at lists.extropy.org> wrote:
> >
> > Anyone have any experience with this?  I have not been tested.
> Apparently you have to ask.  Here's the article from People's Pharmacy:
> >
> >
> https://www.peoplespharmacy.com/articles/is-lpa-the-best-kept-secret-in-heart-disease?
> bill w
> > _______________________________________________
>
>
> The UK is researching this for treatments.
> <https://www.heartuk.org.uk/genetic-conditions/high-lipoproteina>
>
> Quotes:
> Because Lp (a) levels are genetically determined, they do not change
> throughout life and are usually unaffected by diet, lifestyle or
> environment.  Once a Lp (a) level has been measured it does not
> usually need to be checked again.  However it is important to continue
> to monitor and be aware of other modifiable cardiovascular risk
> factors.
> ------
> Currently there are new treatments in clinical trials which stop Lp
> (a) being made at genetic level. There are two treatments - one is
> known as an antisense "oligonucleotide" therapy and the other is known
> as small interfering or siRNA  (gene silencing) treatment.  Both
> treatments prevent the transcription of Lp (a) RNA into the Apo (a)
> protein and reduce Lp (a) production.
> ------------
>
> It's not a secret heart disease in the UK.
>
> BillK
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