[ExI] Jaw-dropping CWRU Alzheimer's breakthrough?

spike spike66 at att.net
Mon Feb 27 03:40:14 UTC 2012


 

 

>. On Behalf Of James Clement
Subject: Re: [ExI] Jaw-dropping CWRU Alzheimer's breakthrough?

 

Spike says:

"This notion can be extended to the kinds of advances we transhumanists
might expect.Wouldn't be fair you know."  

 

 

 

James wrote:


>.It's the 10 years and $800+ Million that it costs to satisfy the FDA that
makes these drugs cost $50000to $100,000 per year. I can bet that the active
ingredients cost no more than a few hundredths of a cent per dose. But to
amortize the cost of approval over the number of expected sales and then
make a profit - that boosts it to this extreme level.

OK thanks James, ja, I agree, and there is nada I can do about that.  Sorry
Eisai, the cat is out of the bag and there is no getting her back in.  There
are plenty of us out here willing to risk a tenth of a milligram of whatever
impurities are in 10 mg of reagent grade bexarotene, going around your
ultra-pure Targretin, sorry.  If I could legally get Targretin, I would use
that, cut it into ten doses (I know how to do that and I have the equipment)
mix that with alcohol to insure it is completely dissolved to the molecular
level, and down the hatch.  I am willing to experiment on myself, before I
suggest it to anyone else.  This is a once in a lifetime opportunity.



>.Short of getting rid of the FDA, one remedy is outright piracy.

Disagree sir, with all due respect, and you know I love you like a brother,
but THIS IS NOT PIRACY to use bexarotene off-label, no sir.  Eisai does not
own that molecule and every use and misuse to which it might be put, no way.
I do respect the notion of intellectual property, but I do not feel it is
stealing anything from Eisai to use reagent grade bex, or Targretin for that
matter.

Thanks for the input James.  Others please?  If you have already hit five
posts today, don't worry about it, I won't notice, and no one is
complaining.  I need guidance riiiiight noooowwwww.  

Dr. Rafal, are ye out there, me lad?

spike

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