[ExI] Fwd: Case A-2643

Rafal Smigrodzki rafal.smigrodzki at gmail.com
Wed Aug 3 07:10:49 UTC 2016


This is a post I tried to send when ExI was down.


---------- Forwarded message ----------
From: Rafal Smigrodzki <rafal.smigrodzki at gmail.com>
Date: Mon, Jul 25, 2016 at 10:05 PM
Subject: Re: [ExI] Case A-2643
To:
Cc: ExI chat list <extropy-chat at lists.extropy.org>




On Mon, Jul 25, 2016 at 10:22 AM, Dylan Distasio <interzone at gmail.com>
wrote:

> I'm a novice on cryonics but why can't a ventricular brain shunt(s) be
> used to perfuse the brain directly, avoiding BBB challenges?
>

### This might be an interesting idea, although a ventricular drain would
be insufficient to perfuse tissue in any reasonable amount of time. You can
deliver medications intrathecally and avoid the BBB but the
intraventricular space does not branch out in the brain tissue like the
vascular system does, so a ventricular perfusion would have to rely on
cryoprotectant diffusion over centimeter scales, which would be
impractical.

A ventricular drain could be used to replace the ventricular fluid with gas
though, and this might help reduce the mechanical strains on brain tissue
during cooling.

I wonder if this was ever considered by Alcor?

Rafał
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